نوع المحرض لالكرمل - sportinzuidhorn About 20% of U.S. health care costs are paid by patients out-of-pocket. 1 During the past 3 decades these costs have grown more than 8-fold from $25.1 billion in 1970 to more than $205 billion in 2001. 2 High out-of-pocket costs are a persistent concern among the public. 3 Furthermore, these costs are associated with medication nonadherence ...